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Study identifier: NCT06995729 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine

Condition: Acute Treatment of Migraine  ·  Sponsor: Pfizer

PhasePhase 1
Planned participants16
Who can joinAll sexes, 6 Years to 11 Years
Healthy volunteersNo

About this study

The purpose of the study is to learn about safety and how the body processes the study medicine called Zavegepant (PF-07930207) in children with a history of migraine. This study helps understand how the medicine is changed and removed from the body after taking it. This study is seeking participants who: * Are children aged between 6 and less than 12 years old * Have had migraine for at least 6 months. * Weigh more than 15 kilograms All participants in this study will receive zavegepant as a nasal spray once (one spray into one nostril). The dose of the study medicine that each participant receives will depend on how much the participant weighs. The study will look at the experiences of the participants receiving the study medicine and collect data to better understand the possible benefits and unwanted effects of different doses of the study medicine. Participants will take part in this study for up to 10 weeks. During this time, they will have 3 study visits at the study clinic, and 2 follow-up phone calls.

This description comes directly from the study's public registry record.

Talk to the study team

Pfizer CT.gov Call Center  ·  1-800-718-1021  ·  ClinicalTrials.gov_Inquiries@pfizer.com

Always discuss trial participation with your own doctor first.

Locations (13)

Arkansas Children's HospitalLittle Rock, Arkansas, United StatesNot Yet Recruiting
Velocity Clinical Research, Washington DCWashington D.C., District of Columbia, United StatesNot Yet Recruiting
Coastal Heritage Clinical ResearchHinesville, Georgia, United StatesRecruiting
Clinical Research InstituteMinneapolis, Minnesota, United StatesNot Yet Recruiting
Children's Hospital & Medical CenterOmaha, Nebraska, United StatesRecruiting
True North NeurologyPort Jefferson Station, New York, United StatesNot Yet Recruiting
Accellacare - PiedmontStatesville, North Carolina, United StatesRecruiting
Accellacare of Piedmont HealthCareStatesville, North Carolina, United StatesRecruiting
Accellacare US Inc.Winston-Salem, North Carolina, United StatesRecruiting
Central States ResearchTulsa, Oklahoma, United StatesRecruiting
Cedar Health ResearchDallas, Texas, United StatesRecruiting
Wasatch Clinical Research, LLCSalt Lake City, Utah, United StatesRecruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06995729