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Study identifier: NCT06995391 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Digitally Rendered Interventions And Knowledge To Limit Ethanol-Associated Atrial Fibrillation Severity

Condition: Atrial Fibrillation (AF)  ·  Sponsor: University of California, San Francisco

PhaseNA
Planned participants1000
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersNo

About this study

Per the 2021 National Survey on Drug Use and Health administered by the U.S. Department of Health and Human Services, 85% of all American adults consume alcohol. Atrial fibrillation (AF) is the most common arrhythmia, affecting more than 10 million individuals in U.S., comprising 4.5% of the adult population. Although alcohol abstinence clearly reduces AF in heavy drinkers, observational data comparing the health effects of limited consumption versus abstention are conflicting. The Mediterranean diet is one of the few that has demonstrated clear cardiovascular benefits in a randomized study-this diet allows for the consumption of red wine (or high polyphenol/ low alcohol alcohol), generally not more than one drink in 24 hours, with meals, avoiding spirits and binge drinking. The effect of the "Mediterranean drinking pattern" on AF risk compared to alcohol abstinence remains unknown. This single center, randomized, controlled trial aims to compare the effects of a digital health intervention to encourage durable alcohol abstinence versus allowing guideline-adherent moderate alcohol consumption on AF severity. The knowledge gained from this study may be used to determine optimal thresholds for alcohol use among AF patients.

This description comes directly from the study's public registry record.

Talk to the study team

Gregory M Marcus, MD, MAS  ·  415-476-5706  ·  greg.marcus@ucsf.edu

Gabrielle C Montenegro, BA  ·  415-502-3053  ·  gabby.montenegro2@ucsf.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UCSF Medical Center at ParnassusSan Francisco, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06995391