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Study identifier: NCT06995118 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Application of "HUAXI Hole 1" in Reverse-sequence Endoscopic Nipple-sparing Mastectomy With Direct-to-implant Breast Reconstruction

Condition: Breast Cancer Early Stage Breast Cancer (Stage 1-3)  ·  Sponsor: Du Zhenggui

PhaseNA
Planned participants337
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

About this study

This study is a multicenter, open-label, randomized controlled trial. It will prospectively compare outcomes between patients undergoing reverse-sequence endoscopic NSM (R-E-NSM) with direct-to-implant breast reconstruction (DIBR) with the "HUAXI Hole 1" versus without the "HUAXI Hole 1". The study aims to evaluate differences in operative efficiency, surgical safety, postoperative aesthetics, and oncological safety between the two groups.

This description comes directly from the study's public registry record.

Talk to the study team

Zhenggui Du, MD  ·  +86 13880768222  ·  docduzg@163.com

Hui Dai, MD  ·  +86 18075202377  ·  daih108@163.com

Always discuss trial participation with your own doctor first.

Locations (20)

Fujian Medical University Union HospitalFuzhou, Fujian, ChinaNot Yet Recruiting
Guangzhou First People's HospitalGuangzhou, Guangdong, ChinaNot Yet Recruiting
Anyang City Tumor HospitalAnyang, Henan, ChinaNot Yet Recruiting
The First Affiliated Hospital of Zhengzhou UniversityZhengzhou, Henan, ChinaNot Yet Recruiting
The First Hospital of Hunan University of Chinese MedicineChangsha, Hunan, ChinaNot Yet Recruiting
The Affiliated Hospital of lnner Mongolia Medical UniversityHohhot, Inner Mongolia, ChinaNot Yet Recruiting
Suzhou Municipal HospitalSuzhou, Jiangsu, ChinaNot Yet Recruiting
Nanchang People's HospitalNanchang, Jiangxi, ChinaNot Yet Recruiting
The First Hospital of Jilin UniversityChangchun, Jilin, ChinaNot Yet Recruiting
Shanxi Bethune HospitalTaiyuan, Shanxi, ChinaNot Yet Recruiting
Taiyuan Central Hospital of Shanxi Medical UniversityTaiyuan, Shanxi, ChinaNot Yet Recruiting
The Fourth People's Hospital of Sichuan ProvinceChengdu, Sichuan, ChinaNot Yet Recruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06995118