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Study identifier: NCT06994975 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

CHinese ischEmic Stroke Beyond 4.5 Hours With TeNecteplase Under Optimized Non-Contrast CT Selection

Condition: Acute Ischemic Stroke  ·  Sponsor: Huashan Hospital

PhasePhase 3
Planned participants890
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The CHESTNUT trial is a multicenter, open-label, blinded-endpoint, randomized, controlled, phase 3 trial. The primary objective of this study is to explore the efficacy and safety of the dose of 0.25 mg/kg tenecteplase (TNK) in Chinese acute ischemic stroke (AIS) patients without substantial infarction on non-contrast computed tomography (NCCT) in an extended time window.

This description comes directly from the study's public registry record.

Talk to the study team

Xin Cheng, MD, PhD  ·  +86 021-52887145  ·  chengxin@fudan.edu.cn

Always discuss trial participation with your own doctor first.

Locations (2)

Huashan HospitalShanghai, Shanghai Municipality, ChinaRecruiting
Huashan Hospital, Fudan UniversityShanghai, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06994975