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Study identifier: NCT06994494 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Noninvasive Continuous BP Monitoring in Newborns Based on Pulsatile Signal Morphological Features Using NIRS

Condition: Unstable Blood Pressure · Hypotension  ·  Sponsor: Massachusetts General Hospital

PhaseN/A
Planned participants80
Who can joinAll sexes, 24 Weeks to 44 Weeks
Healthy volunteersNo

About this study

The goal of this study is to evaluate if a novel near-infrared spectroscopy (NIRS) device can accurately estimate blood pressure in newborns at risk for unstable blood pressure. The main questions it aims to answer are: * Can NIRS accurately estimate blood pressure when compared to the gold standard, arterial line blood pressure * Can NIRS accurately estimate blood pressure when compared to infants with cuff blood pressure monitoring Researchers will compare NIRS-based estimates to arterial line blood pressure readings and manual cuff measurements to optimize and validate the FlexNIRS device for neonates to accurately estimate blood pressure continuously and noninvasively. Participants will wear a small, noninvasive NIRS sensor on the forehead.

This description comes directly from the study's public registry record.

Talk to the study team

Emily M Herzberg, MD  ·  617 724 9040  ·  eherzberg@mgh.harvard.edu

Mohamed A El-Dib, MD  ·  617-732-6902  ·  mel-dib@bwh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (2)

Massachusettes General HospitalBoston, Massachusetts, United StatesRecruiting
Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06994494