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Study identifier: NCT06994403 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Glycemic Response to Carbob-Enriched Pasta in Healthy and With Type 1 Diabetes People

Condition: Glycemic and Insulinemic Response · Type 1 Diabetes (T1D)  ·  Sponsor: Federico II University

PhaseNA
Planned participants10
Who can joinMale, 18 Years to 50 Years
Healthy volunteersYes

About this study

Carob (Ceratonia siliqua) is a fruit traditionally used in various Mediterranean countries for the preparation of sweets and beverages. Its pulp, once the seeds are removed, is milled into carob flour, a nutrient-rich food containing fiber, carbohydrates, proteins, and essential minerals such as potassium, magnesium, sodium, phosphorus, and calcium. Carob flour is also naturally sweet and can serve as a cocoa powder substitute in desserts. Furthermore, it is a source of polyphenols with known antioxidant properties. Clinical evidence suggests that consumption of foods rich in refined carbohydrates is associated with elevated postprandial blood glucose levels, which are recognized as an independent cardiovascular risk factor. The glycemic index (GI) is a useful parameter to assess the impact of carbohydrate-containing foods on postprandial glycemic response. Based on carbohydrate quality, foods are classified as having high, medium, or low GI. Consumption of high-GI foods leads to a stronger glycemic response and has been linked to increased risk of chronic conditions such as type 2 diabetes, obesity, and cardiovascular disease. Given its bromatological profile, carob flour may have the potential to modulate postprandial glycemic responses. However, studies evaluating the GI of carob-based products have shown inconsistent findings. In one randomized trial involving 10 healthy adults, a carob-based snack demonstrated a lower GI (40) compared to a chocolate cookie with an equi…

This description comes directly from the study's public registry record.

Talk to the study team

Lutgarda Bozzetto  ·  +39 3333561105  ·  lutgarda.bozzetto@unina.it

Always discuss trial participation with your own doctor first.

Locations (1)

Federico II UniversityNaples, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06994403