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Study identifier: NCT06991296 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Concentration of n-3 PUFA Monohydroxylated Derivatives in Adults With Obesity After n-3 PUFA Supplementation.

Condition: Obesity  ·  Sponsor: University of North Carolina, Chapel Hill

PhaseNA
Planned participants33
Who can joinAll sexes, 45 Years to 60 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if daily supplementation with SPM Active® can increase omega 3 polyunsaturated fatty acid derivatives and improve well-being in adults with obesity. The main questions it aims to answer are: Does 2 g/day of SPM Active® for 12 weeks increase plasma levels of 14-hydroxydocosahexaenoic (HDHA), 17-HDHA, and 18-hydroxy eicosapentaenoic acid (HEPE)? Does 2 g/day of SPM Active® for 12 weeks improve self-reported burnout, life satisfaction, and sleep quality? Participants will: Take two SPM Active® soft-gel capsules daily for 12 weeks (±2-4 days). Provide 12-hour fasting blood samples before and after the intervention. Complete validated surveys on burnout, life satisfaction, and sleep quality at baseline and study end.

This description comes directly from the study's public registry record.

Talk to the study team

Saame R Shaikh, PhD  ·  317-409-9565  ·  shaikhsa@email.unc.edu

Rafia Virk, MS  ·  7036269517  ·  drvirk@email.unc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UNC Nutrition Research InstituteKannapolis, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06991296