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Study identifier: NCT06991101 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

Condition: Glioblastoma · Brain Cancer · Glioblastoma Multiforme  ·  Sponsor: Baptist Health South Florida

PhasePhase 2
Planned participants190
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this research is to test the safety and effectiveness of the investigational drug ruxolitinib when it is combined with standard of care treatment (radiation therapy and temozolomide) for the treatment of newly diagnosed glioblastoma. Half the people in the study will be assigned to take the study drug ruxolitinib in addition to the standard of care temozolomide and radiation therapy and the other half will be assigned to the standard of care temozolomide and radiation therapy only. This assignment will be randomized in a 1-to-1 ratio, like the flip of a coin.

This description comes directly from the study's public registry record.

Talk to the study team

Manmeet Ahluwalia, M.D., MBA  ·  (786) 596-2000  ·  ManmeetA@baptisthealth.net

MCI Multisite Research Program  ·  MCIMultisiteResearch@baptisthealth.net

Always discuss trial participation with your own doctor first.

Locations (1)

Miami Cancer Institute at Baptist Health, Inc.Miami, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06991101