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Study identifier: NCT06990880 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer

Condition: Neoplasms, Prostate  ·  Sponsor: GlaxoSmithKline

PhasePhase 1/Phase 2
Planned participants85
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of the study is to evaluate how safe and how well the body handles GSK5458514 when administered in participants with prostate cancer. The study will be conducted in two parts - Part 1 (dose escalation phase) and Part 2 (dose expansion phase).

This description comes directly from the study's public registry record.

Talk to the study team

US GSK Clinical Trials Call Center  ·  877-379-3718  ·  GSKClinicalSupportHD@gsk.com

EU GSK Clinical Trials Call Center  ·  +44 (0) 20 89904466  ·  GSKClinicalSupportHD@gsk.com

Always discuss trial participation with your own doctor first.

Locations (19)

GSK Investigational SitePhoenix, Arizona, United StatesRecruiting
GSK Investigational SiteDenver, Colorado, United StatesRecruiting
GSK Investigational SiteNew Haven, Connecticut, United StatesRecruiting
GSK Investigational SiteRochester, Minnesota, United StatesRecruiting
GSK Investigational SiteEast Brunswick, New Jersey, United StatesRecruiting
GSK Investigational SiteNashville, Tennessee, United StatesRecruiting
GSK Investigational SiteMontreal, Quebec, CanadaRecruiting
GSK Investigational SiteMontreal, Quebec, CanadaRecruiting
GSK Investigational SiteLyon, FranceRecruiting
GSK Investigational SiteVillejuif, FranceRecruiting
GSK Investigational SiteKanagawa, JapanRecruiting
GSK Investigational SiteTokyo, JapanRecruiting

+ 7 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06990880