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Study identifier: NCT06990711 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 1 Clinical Trial of Siltuximab for the Treatment of Antibody-Mediated Rejection After Lung Transplantation

Condition: Antibody Mediated Rejection of Lung Transplant  ·  Sponsor: Washington University School of Medicine

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Antibody-mediated rejection after lung transplantation commonly results in allograft failure and death in spite of current therapeutic regimens. We are testing the safety and tolerability of the addition of a novel immunosuppressive medication to routine treatment for antibody-mediated rejection. Future studies will be needed to assess efficacy if this study demonstrates safety

This description comes directly from the study's public registry record.

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Contact details are listed per location below or on the registry record.

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Locations (2)

Washington University School, of Medicine, Barnes-Jewish HospitalSt Louis, Missouri, United StatesRecruiting
University of UtahSaint Lake City, Utah, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06990711