Condition: ARDS (Acute Respiratory Distress Syndrome) · Sponsor: Southeast University, China
Acute respiratory syndrome distress (ARDS) is a clinical common syndrome with high mortality. Mechanical ventilation (MV) is the cornerstone of management of ARDS but can lead to ventilator-induced lung injury. Positive end-expiratory pressure (PEEP), as one of main component of MV, has been widely used in the clinical practice. However, the PEEP selection is still a difficult problem for moderate to severe ARDS patients. EIT, an imaging tool evaluating the regional ventilation distribution at the bedside, can achieve the individual PEEP selection for all mechanically ventilated patients. Our previous study found that moderate to severe ARDS patients with higher recruitability could benefit from EIT-guided PEEP. This article compared the effect of PEEP titrated guided by EIT with fraction of inspired oxygen (FiO2)-PEEP table on the clinical outcomes in ARDS patients.
This description comes directly from the study's public registry record.
yuan xue yan, MD, MD · +86 83262550 · 18826401594@163.com
Always discuss trial participation with your own doctor first.
| Second Hospital of Anhui Medical University | Hefei, Anhui, China | Not Yet Recruiting |
| Department of Critical Care Medicine, Zhongshan Hospital of Fudan University | Shanghai, China Mainland, China | Recruiting |
| Department of Critical Care Medicine, Renji Hospital | Shanghai, China Mainland, China | Not Yet Recruiting |
| The First Affiliated Hospital of Guangzhou Medical University | Guangzhou, Guangdong, China | Not Yet Recruiting |
| Zhengzhou Central Hospital Affiliated to Zhengzhou University | Zhengzhou, Henan, China | Not Yet Recruiting |
| The Affiliated Hospital of Hangzhou Normal University | Hangzhou, Jiangsu, China | Not Yet Recruiting |
| Zhongda Hospital, School of Medicine, Southeast University | Nanjing, Jiangsu, China | Recruiting |
| The Affiliated Hospital of Xuzhou Medical University | Xuzhou, Jiangsu, China | Not Yet Recruiting |
| The First Affiliated Hospital of Nanchang University | Nanchang, Jiangxi, China | Not Yet Recruiting |
| Qinghai University Affiliated Hospital | Xining, Qinghai, China | Not Yet Recruiting |
| First Affiliated Hospital of Xi'an Jiaotong University | Xian, Shanxi, China | Not Yet Recruiting |
| People's Hospital of Quzhou | Quzhou, Zhejiang, China | Not Yet Recruiting |
+ 5 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06990477