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Study identifier: NCT06990087 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

T-cell Therapy in Patients With PML

Condition: Progressive Multifocal Leucoencephalopathy (PML)  ·  Sponsor: Hannover Medical School

PhasePhase 2
Planned participants23
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

There is no approved standard treatment für progressive multifocal leukoencephalopathy (PML). The sponsor of the study is developing a new treatment. For this reason, the investigational medicinal product (IMP) called 'human allogenic HPyV-2-specific T cells' is to be tested in this study. The sponsor wants to find out whether the IMP is safe, influences the neurological status and improves the quality of the life of patients . It is to be investigated whether the IMP can be used to treat the disease and whether it could have an advantage over the standard therapy in terms of survival rate.

This description comes directly from the study's public registry record.

Talk to the study team

Thomas Skripuletz, Prof. Dr.  ·  +49 511 532  ·  skripuletz.thomas@mh-hannover.de

Always discuss trial participation with your own doctor first.

Locations (6)

LMU Klinikum Campus GroßhadernMünchen, Bavaria, GermanyNot Yet Recruiting
Universitätsklinikum MarburgMarburg, Hesse, GermanyNot Yet Recruiting
Hannover Medical SchoolHanover, Lower Saxony, GermanyRecruiting
Universitätsklinikum DüsseldorfDüsseldorf, North Rhine-Westphalia, GermanyNot Yet Recruiting
Universitätsklinikum EssenEssen, North Rhine-Westphalia, GermanyNot Yet Recruiting
Universitätsklinikum Schleswig-HolsteinKiel, Schleswig-Holstein, GermanyNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06990087