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Study identifier: NCT06989905 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

MEP Up-conditioning to Target Corticospinal Plasticity

Condition: Spinal Cord Injury · Tetraplegia/Tetraparesis  ·  Sponsor: Medical University of South Carolina

PhaseEARLY_Phase 1
Planned participants11
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Individuals with chronic cervical spinal cord injury will complete a 10-week training protocol where participants receive non-invasive brain stimulation and feedback on the size of the corresponding muscle response (wrist extensor). Investigators will assess the impact of the brain stimulation training on 1) the brain-to-spinal cord-to-muscle connection and 2) motor functions of the arm and hand. Also, brain and spine magnetic resonance imaging will be collected before and after the training. The imaging measurements will tell investigators about how spinal damage, brain function, and brain structure relate to motor presentation and the response to the training.

This description comes directly from the study's public registry record.

Talk to the study team

Recruitment Contact  ·  843-792-6313  ·  stecb@musc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06989905