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Study identifier: NCT06989840 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne

Condition: Acne  ·  Sponsor: Sagimet Biosciences Inc.

PhasePhase 1
Planned participants128
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersYes

About this study

This is a 4-part study. Part A will be a randomized, double-blind, placebo-controlled investigation of single ascending doses (SAD) to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) biomarkers of TVB-3567 administered orally in healthy participants. Part B will be a randomized, open-label, 2-way crossover investigation to assess the effect of food on a single dose TVB-3567 administered orally in healthy participants. Parts C and D will be randomized, double-blind, placebo-controlled investigations of multiple ascending doses (MAD) to assess the safety, tolerability, PK, and PD/biomarkers of TVB-3567 administered orally in healthy participants without and with moderate to severe acne, respectively.

This description comes directly from the study's public registry record.

Talk to the study team

Study Director  ·  (650) 561-8600  ·  SB3567-CLIN-001@sagimet.com

Always discuss trial participation with your own doctor first.

Locations (2)

Celerion, Inc.Tempe, Arizona, United StatesCompleted
Nucleus NetworkMelbourne, Victoria, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT06989840