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Study identifier: NCT06989723 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pioglitazone and Empagliflozin for Fatty Liver Disease in Type 2 Diabetes

Condition: Type 2 Diabetes · Fatty Liver  ·  Sponsor: Seoul National University Bundang Hospital

PhasePhase 4
Planned participants120
Who can joinAll sexes, 20 Years to no upper limit
Healthy volunteersNo

About this study

This exploratory study will assess the efficacy of combined pioglitazone and empagliflozin therapy in improving hepatic and metabolic outcomes in patients with type 2 diabetes mellitus and metabolic dysfunction-associated fatty liver disease (MAFLD). Although each agent has shown beneficial effects individually, evidence on their combined impact on liver health is scarce. This study seeks to determine whether the combination therapy yields additive improvements in hepatic steatosis, inflammation, and fibrosis, potentially offering a new therapeutic strategy for diabetic patients with fatty liver disease.

This description comes directly from the study's public registry record.

Talk to the study team

Soo Lim Dr, MD PhD  ·  +82-31-787-7035  ·  limsoo@snu.ac.kr

Minji Sohn Dr, PhD  ·  rainbowmjs@naver.com

Always discuss trial participation with your own doctor first.

Locations (1)

Seoul National University Bundang HospitalSeongnam-si, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT06989723