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Study identifier: NCT06989437 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

Condition: Cachexia · Metastatic Pancreatic Ductal Adenocarcinoma  ·  Sponsor: Pfizer

PhasePhase 2/Phase 3
Planned participants982
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Study to investigate the efficacy, safety and tolerability of systemic chemotherapy plus ponsegromab versus systemic chemotherapy plus placebo for the first-line treatment in adult participants with cachexia and metastatic pancreatic ductal adenocardinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Pfizer CT.gov Call Center  ·  1-800-718-1021  ·  ClinicalTrials.gov_Inquiries@pfizer.com

Always discuss trial participation with your own doctor first.

Locations (214)

The Kirklin Clinic of UAB HospitalBirmingham, Alabama, United StatesRecruiting
The University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
Mayo Clinic HospitalPhoenix, Arizona, United StatesNot Yet Recruiting
Central Arkansas Radiation Therapy Institute, dba CARTIBryant, Arkansas, United StatesRecruiting
Central Arkansas Radiation Therapy Institute, dba CARTIConway, Arkansas, United StatesRecruiting
CARTI Cancer CenterLittle Rock, Arkansas, United StatesRecruiting
Central Arkansas Radiation Therapy Institute, dba CARTINorth Little Rock, Arkansas, United StatesRecruiting
Central Arkansas Radiation Therapy Institute, dba CARTIPine Bluff, Arkansas, United StatesRecruiting
UC San Diego Medical Center - EncinitasEncinitas, California, United StatesRecruiting
Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine, California, United StatesRecruiting
UCI Health - IrvineIrvine, California, United StatesRecruiting
UC San Diego Koman Family Outpatient PavilionLa Jolla, California, United StatesRecruiting

+ 202 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06989437