● Recruiting

A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

Condition: Polycythemia Vera (PV) · Sponsor: Disc Medicine, Inc

PhasePhase 2

Planned participants60

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

This open-label, multicenter, within-participant dose escalation study examining up to 2 dose levels of DISC-3405 will assess the safety, tolerability, efficacy, pharmacokinetics, and pharmacodynamics of DISC-3405 in participants with polycythemia vera (PV).

This description comes directly from the study's public registry record.

Talk to the study team

Disc Medicine Clinical Trials · (617) 674 9274 · clinicaltrials@discmedicine.com

Always discuss trial participation with your own doctor first.

Locations (15)

Mayo Clinic in Arizona	Phoenix, Arizona, United States	Recruiting
USC Norris Comprehensive Cancer Center	Los Angeles, California, United States	Recruiting
UCLA Health	Los Angeles, California, United States	Recruiting
Keck Medicine of USC - Cancer Clinic- Newport Beach	Newport Beach, California, United States	Recruiting
Mayo Clinic in Florida	Jacksonville, Florida, United States	Recruiting
Mayo Clinic in Minnesota	Rochester, Minnesota, United States	Recruiting
Siteman Cancer Center - Washington University St. Louis	St Louis, Missouri, United States	Recruiting
Atrium Health - Levine Cancer Center	Charlotte, North Carolina, United States	Recruiting
Duke University	Durham, North Carolina, United States	Recruiting
Atrium Health Wake Forest Baptist Medical Center	Winston-Salem, North Carolina, United States	Recruiting
Cleveland Clinic	Cleveland, Ohio, United States	Recruiting
Ohio State University	Columbus, Ohio, United States	Recruiting

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06985147