Condition: Type 2 Diabetes Mellitus (T2DM) · Metabolic Dysfunction-Associated Steatotic Liver Disease · Biological Age · Sponsor: Ningbo No. 1 Hospital
The association between biological aging and type 2 diabetes mellitus (T2DM) incidence in individuals with and without metabolic dysfunction-associated steatotic liver disease (MASLD) remains unclear.We assessed biological age by calculating phenotypic age (PhenoAge), Klemera-Doubal method (KDMAge), and homeostatic dysregulation (HDAge). To examine the association of biological ageing with the risk of T2DM, cox regression models were conducted. Furthermore, we applied survival analysis, restricted cubic spline models and population attributable fraction (PAF) to further evaluate the association between biological ageing and T2DM incidence.
This description comes directly from the study's public registry record.
Lei Xu · +8613486659126 · xulei22@163.com
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| the First Affiliated Hospital of Ningbo University Ningbo, Zhejiang, China, 315000 | Ningbo, Zhejiang, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06984510