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Study identifier: NCT06983678 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neural Correlates and Behavioral Impact of Withdrawal-induced Hyperalgesia Among People Who Smoke With and Without Chronic Pain

Condition: Tobacco Use · Chronic Pain  ·  Sponsor: Duke University

PhaseNA
Planned participants132
Who can joinAll sexes, 21 Years to 65 Years
Healthy volunteersNo

About this study

Individuals with chronic pain are more likely to smoke cigarettes and have more difficulty quitting smoking than the general population, in part because withdrawal from smoking can lead to temporary increases in pain. This research will examine how smoking withdrawal changes the way the brain processes pain, and whether these withdrawal-related changes interfere with the ability to stop smoking. The results of this research will provide important information that can be used to guide the development of interventions to help people with chronic pain who smoke cigarettes to quit smoking and improve their health.

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Research Coordinator  ·  919-907-9955  ·  sweitzerlab@duke.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Duke North PavilionDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06983678