Condition: CCM · Familial Cerebral Cavernous Malformation · Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Patients with symptomatic and asymptomatic familial cerebral cavernous malformation (fCCM) will be included. The goal of this observational study is to learn about the long-term evolution of this condition. The subjects enrolled will be followed for two years and will undergo an annual neurological examination with the recording of clinical events, a brain MRI according to a dedicated protocol, and a blood draw for the determination of circulating biomarkers. They will also be asked to complete questionnaires on quality of life. The data derived from the study will allow for a better understanding of the natural history of the disease and the identification of neuroradiological and/or circulating biomarkers capable of predicting the clinical evolution of the condition.
This description comes directly from the study's public registry record.
Silvia Lanfranconi, MD, Neurologist · +390255033802 · silvia.lanfranconi@policlinico.mi.it
Always discuss trial participation with your own doctor first.
| Policlinico di Bari | Bari, Italy | Not Yet Recruiting |
| Careggi Hospital, Firenze | Florence, Italy | Recruiting |
| Istituto Giannina Gaslini, Genova | Genova, Italy | Not Yet Recruiting |
| Fondazione IRCCS Cà Granda, Ospedale Maggiore Policlinico, Milan, Italy | Milan, Italy | Recruiting |
| Istituto di Ricerche Farmacologiche Mario Negri | Milan, Italy | Active Not Recruiting |
| San Giovanni di Dio e Ruggi d'Aragona", Salerno | Salerno, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06983132