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Study identifier: NCT06982274 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Oral Arsenic With ATRA for Newly Diagnosed Patients With Acute Promyelocytic Leukemia

Condition: Acute Promyelocytic Leukemia (APL)  ·  Sponsor: Instituto do Cancer do Estado de São Paulo

PhasePhase 2
Planned participants115
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

It is a non-randomized, multicenter, prospective study, aiming to treat patients with newly diagnosed acute promyelocytic leukemia with a combination of oral arsenic and atra, with low dose chemotherapy for those with high-risk disease (white blood cell count above 10x10a9/L). The primary objective is to assess the 2-year overall survival (OS) in these patients, comparing with the historical control group of patients treated with ATRA/chemotherapy according to the IC-APL 2006 protocol.

This description comes directly from the study's public registry record.

Talk to the study team

Elaine Uehara  ·  55 38933535  ·  elaine.uuehara@hc.fm.usp.br

Always discuss trial participation with your own doctor first.

Locations (1)

Instituto do Cancer do Estado de Sao PauloSão Paulo, São Paulo, BrazilRecruiting

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Source record: clinicaltrials.gov/study/NCT06982274