Condition: Aedes-borne Diseases · Sponsor: Institute of Tropical Medicine, Belgium
Arboviral diseases are viral diseases transmitted by mosquitoes of the Aedes genus and are constantly spreading throughout the world, constituting a significant threat to public health. In Africa, there is very little data on the epidemiological situation of Aedes-borne diseases and programs for monitoring these diseases are very limited. In the Democratic Republic of the Congo (DRC), several epidemics of yellow fever, dengue fever, chikungunya and Zika cases have been reported. In particular, in Kinshasa, the dengue and chikungunya viruses have previously been detected in patients with undifferentiated fevers and several studies have shown entomological transmission indices above the criteria and standards of the World Health Organization (WHO). The aim of our study is to implement and evaluate different strategies to control Aedes mosquitoes at different stages of their life cycle in the city of Kinshasa. In particular, a before-and-after interventional study will be piloted and tested in the health zone of Kinshasa, with the aim of providing preliminary evidence of the impact of vector control tools. Interventions will be implemented in 400 households for each arm for 12 months. Before, after and during the interventions, entomological surveys will be conducted in 160 households in each arm to define the density of the vectors. Mosquitoes will be tested for the possible presence of arbovirus RNA (dengue, chikungunya, Zika, yellow fever). During the pre-intervention per…
This description comes directly from the study's public registry record.
Luciana Lepore · +32(0)32476666 · llepore@itg.be
Wim Van Bortel · +32(0)32476666 · wvanbortel@itg.be
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| Institut National de Recherche Biomédicale, INRB | Kinshasa, République Démocratique Du Congo, Democratic Republic of the Congo | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06981442