Condition: Hysterectomy · PVI · Fluid Responsiveness · Sponsor: Wonkwang University Hospital
This observational study investigates the predictors of Pleth Variability Index (PVI) changes in euvolemic patients undergoing laparoscopic-assisted vaginal hysterectomy (LAVH). The primary objective is to quantify changes in PVI (ΔPVI) across six intraoperative time points associated with positional shifts. Secondary objectives include identifying key predictors of significant PVI change (ΔPVI ≥ 5%), such as passive leg raising, Trendelenburg position, body mass index (BMI), and intraabdominal pressure. Additional variables including perfusion index, mean arterial pressure, bispectral index, skin temperature, age, and anesthetic agent will be evaluated as potential modulators. Findings aim to support individualized fluid management strategies in LAVH.
This description comes directly from the study's public registry record.
Cheol Lee, M.D.,Ph.D · 01066131252 · ironyii@wku.ac.kr
Cheolhyeong Lee, M.D. · 01066131252 · Leecheolhyeong@gmail.com
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| Wonkwang University School of Medicine Hospital | Iksan, Jeollabuk-do, South Korea | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06981221