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Study identifier: NCT06980584 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study on the Treatment of Nonthrombotic Obstructive Pulmonary Hypertension

Condition: Fibrosing Mediastinitis · Pulmonary Hypertension  ·  Sponsor: Beijing Chao Yang Hospital

PhaseNA
Planned participants48
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

Through a randomized controlled trial (RCT) design, this study aiming to evaluated the efficacy and safety of rituximab lymph node injection combined with pulmonary vascular interventional therapy in treating fibrosing mediastinal pulmonary hypertension (FM-PH).Eligible participants were randomly assigned to either the combined treatment group, receiving both pulmonary vascular intervention and rituximab lymph node injection, or the interventional-only group, which received pulmonary vascular intervention alone. At 3, 6, and 12 months post-treatment, the efficacy was assessed based on symptom improvement, hemodynamic changes, lesion volume reduction, etc. Safety was mainly evaluated by comparing adverse event incidence between the two groups.

This description comes directly from the study's public registry record.

Talk to the study team

Juanni Gong, Doctor of Medicine  ·  15801511482  ·  juannigong2018@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Chaoyang Hospital, Capital Medical UniversityBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06980584