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Study identifier: NCT06980025 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

Condition: Preterm Delivery · Obstetrical Complications  ·  Sponsor: The George Washington University Biostatistics Center

PhasePhase 3
Planned participants1800
Who can joinFemale, 14 Years to no upper limit
Healthy volunteersYes

About this study

This is a phase-III multi-center double-blind randomized clinical trial of 1,800 individuals with a history of prior preterm birth at less than 35 weeks gestation who are randomized to either 162 mg aspirin or 81 mg aspirin daily. The study drug will be initiated between 10 and 15 weeks gestation and continued through 36 weeks, 6 days gestation. The primary endpoint is recurrent preterm delivery or fetal death prior to 35 weeks, 0 days gestation.

This description comes directly from the study's public registry record.

Talk to the study team

Rebecca G Clifton, PhD  ·  (301) 881-9260  ·  rclifton@bsc.gwu.edu

Trisha Boekhoudt, MPH  ·  trishab@bsc.gwu.edu

Always discuss trial participation with your own doctor first.

Locations (14)

University of Alabama - BirminghamBirmingham, Alabama, United StatesRecruiting
Regents of the University of California San FranciscoSan Francisco, California, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
Columbia UniversityNew York, New York, United StatesRecruiting
University of North Carolina - Chapel HillChapel Hill, North Carolina, United StatesRecruiting
Duke UniversityDurham, North Carolina, United StatesRecruiting
Case Western Reserve UniversityCleveland, Ohio, United StatesRecruiting
Ohio State UniversityColumbus, Ohio, United StatesRecruiting
Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
Magee Women's Hospital of UPMCPittsburgh, Pennsylvania, United StatesRecruiting
Brown UniversityProvidence, Rhode Island, United StatesRecruiting
Baylor College of MedicineHouston, Texas, United StatesRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06980025