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Study identifier: NCT06979596 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)

Condition: Malignant Neoplasm  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 2
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Researchers want to learn if MK-5684 (the study medicine) can treat breast cancer, ovarian cancer, and endometrial cancer. MK-5684, the study medicine, is designed to treat cancer by blocking the body from making steroid hormones. Researchers will compare MK-5684 to the standard treatments for each cancer type in this study. The goal of this study is to learn if people who receive MK-5684 live longer without the cancer growing or spreading compared to people who receive a standard treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Toll Free Number  ·  1-888-577-8839  ·  Trialsites@msd.com

Always discuss trial participation with your own doctor first.

Locations (58)

Alaska Womens Cancer Care ( Site 0037)Anchorage, Alaska, United StatesRecruiting
Mount Sinai Cancer Center ( Site 0009)Miami Beach, Florida, United StatesRecruiting
TRIALS 365 ( Site 0022)Shreveport, Louisiana, United StatesRecruiting
Mary Lanning Healthcare ( Site 0019)Hastings, Nebraska, United StatesRecruiting
John Theurer Cancer Center at Hackensack University Medical Center ( Site 0021)Hackensack, New Jersey, United StatesRecruiting
Rockefeller Outpatient Pavilion ( Site 0002)New York, New York, United StatesRecruiting
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 0008)Columbus, Ohio, United StatesRecruiting
Baylor College of Medicine Medical Center ( Site 0004)Houston, Texas, United StatesRecruiting
Harris Health System ( Site 0040)Houston, Texas, United StatesRecruiting
Mays Cancer Center ( Site 0039)San Antonio, Texas, United StatesRecruiting
Hospital Aleman ( Site 0301)Ciudad Autonoma de Buenos Aires, Buenos Aires, ArgentinaRecruiting
Centro Medico Dr. Doreski - Fundación Respirar ( Site 0302)Buenos Aires, Buenos Aires F.D., ArgentinaRecruiting

+ 46 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06979596