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Study identifier: NCT06979336 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

Condition: Ulcerative Colitis  ·  Sponsor: Genentech, Inc.

PhasePhase 2
Planned participants224
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy of RO7837195 compared with placebo in participants with moderately to severely active ulcerative colitis for whom prior treatment with conventional and/or advanced therapies has failed.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: GA45977 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S.)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (103)

Gastro Care InstituteLancaster, California, United StatesRecruiting
Medical Associates Research Group, Inc.San Diego, California, United StatesRecruiting
Peak Gastroenterology AssociatesColorado Springs, Colorado, United StatesRecruiting
Clinical Research of Osceola, LLCKissimmee, Florida, United StatesRecruiting
University of Chicago Medical CenterChicago, Illinois, United StatesRecruiting
Intercity GastroenterologyFresh Meadows, New York, United StatesRecruiting
Monroe Biomedical ResearchMonroe, North Carolina, United StatesRecruiting
University of Utah Hospitals & ClinicsSalt Lake City, Utah, United StatesRecruiting
Mater Misericordiae LimitedSouth Brisbane, Queensland, AustraliaRecruiting
HUWC - UFC - Hospital Universitrio Walter Cantdio - Universidade Federal do CearFortaleza, Ceará, BrazilRecruiting
L2IP ?Instituto de Pesquisas Clínicas Ltda.Brasília, Federal District, BrazilRecruiting
Chronos Pesquisa ClinicaBrasília, Federal District, BrazilRecruiting

+ 91 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06979336