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Study identifier: NCT06978400 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Dabrafenib Plus Cetuximab/Panitumumab With FOLFOX in the First Line of Therapy in People With Metastatic Colorectal Cancer

Condition: Neoplasms  ·  Sponsor: Blokhin's Russian Cancer Research Center

PhasePhase 2
Planned participants64
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy and toxicity of FOLFOX regimen with dabrafenib and cetuximab/panitumumab in the first line of therapy for the potential treatment of colorectal cancer that: has a metastatic, inoperable; has a mutation in the BRAF gene and MSS. Participants in this study will receive one of the following study treatments: These participants will receive FOLFOX regimen with dabrafenib and cetuximab or panitumumab in the first line of therapy This study is currently enrolling participants who will receive either FOLFOX regimen with dabrafenib and cetuximab or panitumumab in the first line of therapy. The study team will monitor how each participant responds to the study treatment for up to about 3 years.

This description comes directly from the study's public registry record.

Talk to the study team

Mikhail Fedyanin MD  ·  +7 905 704-33-18  ·  fedianinmu@mail.ru

Evgenia Kuzmina MD  ·  +7 9824012681  ·  kuz011@mail.ru

Always discuss trial participation with your own doctor first.

Locations (1)

Blokhin's Russian Cancer Research CenterMoscow, RussiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06978400