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Study identifier: NCT06976671 Synced from ClinicalTrials.gov · July 29, 2026
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A Study to Determine the Safety and Efficacy of Bevacizumab Administered Via Injection Into the Shoulder Joint of Participants With Adhesive Capsulitis (Frozen Shoulder)

Condition: Adhesive Capsulitis  ·  Sponsor: Macquarie University, Australia

PhasePhase 2
Planned participants28
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is intended to test a new treatment for a condition called adhesive capsulitis, also known as frozen shoulder. The treatment being tested is called bevacizumab. Participants will receive a single dose of bevacizumab (50mg, 100mg, 150mg, or 200mg) via injection into their shoulder joint. After the injection, participants will return to site 6 times over the course of a year for safety assessments, questionnaires to track pain levels, and range of movement tests conducted by a physiotherapist. The main goal of this study is to: 1. Evaluate the safety and effectiveness of bevacizumab when it is injected into the frozen shoulder joint. 2. Determine the maximum dose of bevacizumab that can be given without side effects. This is an investigator initiated clinical trial sponsored by Macquarie University. There will be a maximum of 28 participants enrolled and the only site involved in recruitment is Macquarie University.

This description comes directly from the study's public registry record.

Talk to the study team

Sumit Raniga, BSC, MSC, MBCHB, FRACS, FAORTH  ·  +61 2 9812 3583  ·  sumit.raniga@mqhealth.org.au

Always discuss trial participation with your own doctor first.

Locations (1)

Macquarie UniversityNorth Ryde, New South Wales, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT06976671