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Study identifier: NCT06975683 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Open, Non-comparative Pilot Study to Evaluate the Safety and Efficacy of Intraovarian Plasma Rich in Growth Factors (PRGF) in Patients With Low Ovarian Reserve

Condition: Low Ovarian Reserve  ·  Sponsor: Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz

PhaseNA
Planned participants50
Who can joinFemale, 18 Years to 50 Years
Healthy volunteersNo

About this study

The use of plasma rich in growth factors (PRGF) improves ovarian reserve markers and IVF laboratory parameters in women with low ovarian reserve. Primary objective To compare ovarian reserve markers and IVF-ICSI laboratory results before and after PRGF infusion. Secondary Objectives * To compare pre- and post-treatment pregnancy rates. * To collect complications associated with the application of intraovarian PRGF. General Outline of the Study VISIT 1 * Patient Selection * Confirm that he/she has all the analyses and variables to be studied. * Signing of Informed Consent * Usual IVF protocol (1st IVF cycle) VISIT 2 * Instillation of intraovarian PRGF on the day of the puncture of the 1st IVF cycle in the FJD VISIT 3 * Analytical control at 4 weeks VISIT 4 * Analytical control at 8 weeks VISIT 5 * In case of failure to achieve gestation Start of 2nd cycle of IVF

This description comes directly from the study's public registry record.

Talk to the study team

Carlos Javier Valdera Simbron  ·  915504800  ·  carlos.valdera@fjd.es

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital Universitario Fundación Jiménez DiazMadrid, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT06975683