● Recruiting

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

Condition: Advanced Solid Tumor · Metastatic Solid Tumor · Endometrial Cancer · Sponsor: MOMA Therapeutics

PhasePhase 1

Planned participants132

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

This Phase 1, multi-center, open-label, dose escalation and dose optimization study is designed to assess the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PDx), and preliminary clinical activity of MOMA-341 administered orally as a single agent or combination therapy in patients with microsatellite instability high (MSI-H) or DNA mismatch repair deficiency (dMMR) solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

MOMA Clinical Trials · 857-285-3677 · clinicaltrials@momatx.com

Always discuss trial participation with your own doctor first.

Locations (15)

Investigative Site #132	Phoenix, Arizona, United States	Recruiting
Investigative Site #101	San Diego, California, United States	Recruiting
Investigative Site #128	Tampa, Florida, United States	Recruiting
Investigative Site #120	Detroit, Michigan, United States	Recruiting
Investigative Site #110	St Louis, Missouri, United States	Recruiting
Investigative Site #131	Raleigh, North Carolina, United States	Recruiting
Investigative Site #121	Portland, Oregon, United States	Recruiting
Investigative Site #127	Dallas, Texas, United States	Completed
Investigative Site #129	Houston, Texas, United States	Recruiting
Investigative Site #122	Sydney, New South Wales, Australia	Recruiting
Investigative Site #123	Westmead, New South Wales, Australia	Recruiting
Investigative Site #124	Woolloongabba, Queensland, Australia	Completed

+ 3 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06974110