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Study identifier: NCT06973590 Synced from ClinicalTrials.gov · July 29, 2026
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Blood Flow Restriction and Transcutaneous Electrical Nerve Stimulation on Motor Function in Stroke

Condition: Chronic Stroke  ·  Sponsor: The Hong Kong Polytechnic University

PhaseNA
Planned participants80
Who can joinAll sexes, 50 Years to 80 Years
Healthy volunteersNo

About this study

Stroke commonly results in persistent leg impairments that limit mobility and reduce quality of life. This study investigates whether combining low-intensity resistance training with blood flow restriction (LIRT-BFR) and transcutaneous electrical nerve stimulation (TENS) can effectively improve leg function in stroke survivors. Participants with chronic stroke will be randomly assigned to one of four intervention groups: 1) LIRT with simulated BFR and simulated TENS; 2) LIRT with actual BFR and simulated TENS; 3) LIRT with simulated BFR and actual TENS; 4) LIRT with both actual BFR and actual TENS. The resistance training utilizes 20% of each participant's maximum lifting capacity. For blood flow restriction, an automated pressure cuff (SmartCuffs 4.0) will be placed on the upper portion of the affected leg, inflated to 50% of the individual's occlusion pressure during exercises and deflated during rest periods. TENS therapy delivers controlled electrical impulses through electrodes positioned on the anterior thigh. Each 60-minute session includes a 10-minute warm-up followed by 40 minutes of targeted resistance exercises (leg extensions, leg presses, and weight-bearing squats) and concludes with 10 minutes of stationary cycling. The resistance protocol involves 3 sets of 20 repetitions with standardized rest intervals between sets and exercises. Participants will attend three sessions weekly for six weeks. Assessments will be conducted at baseline, midpoint (3 weeks), com…

This description comes directly from the study's public registry record.

Talk to the study team

Shamay NG, PhD  ·  +852 27664889  ·  shamay.ng@polyu.edu.hk

Always discuss trial participation with your own doctor first.

Locations (1)

The Hong Kong Polytechnic UniversityHong Kong, Hong KongRecruiting

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Source record: clinicaltrials.gov/study/NCT06973590