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Study identifier: NCT06972628 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Treatment of Patients With Progressive mCRPC With 177Lu-PSMA-617

Condition: Metastatic Castration-Resistant Prostate Cancer · Prostate Cancer Patients With Bone Metastasis · Prostate Cancer (CRPC)  ·  Sponsor: Ebrahim S Delpassand

PhasePhase 2
Planned participants30
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and tolerability of Lutetium-177-PSMA-617 (PLUVICTO) in patients with metastatic castration-resistant prostate cancer (mCRPC) and extensive bone metastases, which appear as a "super scan" pattern on a bone scan. Pluvicto is FDA-approved, but patients with super scan bone scans were previously excluded from the VISION clinical trial, leaving a knowledge gap. The study will enroll up to 30 men with metastatic castration-resistant prostate cancer, with an initial dosing approach that differs from the standard dose. The safety and tolerability of PLUVICTO will be evaluated in this study, with a focus on identifying the optimal dose for this population. This study addresses an important gap in understanding how Pluvicto performs in mCRPC patients with super scan findings.

This description comes directly from the study's public registry record.

Talk to the study team

Susan Cork Therapy Coordinator  ·  713-781-6200  ·  scork@exceldiagnostics.com

Nereyda Sauceda, Therapy Coordinator  ·  713-781-6200  ·  nsauceda@exceldiagnostics.com

Always discuss trial participation with your own doctor first.

Locations (1)

Excel Diagnostics & Nuclear Oncology CenterHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06972628