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Study identifier: NCT06972069 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Tolerance Through Mixed Chimerism (Sip-Tego)

Condition: Kidney Failure · Transplant Recipient (Kidney) · Transplant Tolerance  ·  Sponsor: Tatsuo Kawai, MD, PhD

PhaseEARLY_Phase 1
Planned participants12
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This is an open-label, single-institution study to assess the safety and the efficacy of the Sip-Tego regimen for the induction of donor-specific immunologic unresponsiveness to a renal allograft. The investigators propose to treat 6 adult subjects in end-stage renal disease (ESRD) who do not demonstrate evidence of prior sensitization.

This description comes directly from the study's public registry record.

Talk to the study team

Kerry Augusta, RN  ·  617-724-8570  ·  kaugusta@mgb.org

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06972069