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Study identifier: NCT06971939 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

Condition: Macular Telangiectasia Type 2 (MacTel)  ·  Sponsor: Neurotech Pharmaceuticals

PhasePhase 4
Planned participants285
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this global, multicenter, open-label, Phase 4 clinical extension study is to evaluate the long-term safety and efficacy of revakinagene taroretcel-lwey (Encelto™; hereinafter referred to as NT-501), in participants with macular telangiectasia type 2 (MacTel) who previously received the intraocular implant in a Phase 1, Phase 2, or Phase 3 clinical study. In addition, this study will evaluate the safety and efficacy of NT501 in participants who previously underwent the sham procedure in a Phase 3 MacTel clinical study and elect to have NT-501 implanted intraocularly in this Phase 4 study.

This description comes directly from the study's public registry record.

Talk to the study team

Patricia Davis  ·  401-333-3880  ·  p.davis@neurotechusa.com

Always discuss trial participation with your own doctor first.

Locations (26)

Scripps HealthLa Jolla, California, United StatesNot Yet Recruiting
Jules Stein Eye Institute/UCLALos Angeles, California, United StatesNot Yet Recruiting
Stanford University School of MedicinePalo Alto, California, United StatesNot Yet Recruiting
Bay Area Retina AssociatesWalnut Creek, California, United StatesRecruiting
Colorado RetinaLakewood, Colorado, United StatesNot Yet Recruiting
Bascom PalmerMiami, Florida, United StatesNot Yet Recruiting
Emory Eye CenterAtlanta, Georgia, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
National Eye InstituteBethesda, Maryland, United StatesNot Yet Recruiting
Cumberland Valley Retina ConsultantsFrederick, Maryland, United StatesNot Yet Recruiting
Massachusetts Eye and Ear Infirmary, Retina ServiceBoston, Massachusetts, United StatesNot Yet Recruiting
Foundation for Vision ResearchGrand Rapids, Michigan, United StatesRecruiting

+ 14 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06971939