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Study identifier: NCT06969092 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study on the Correlation Between Oral Health and Delirium in Surgical Inpatients

Condition: Oral Health  ·  Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

PhaseN/A
Planned participants550
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

Delirium is a clinical syndrome characterized by acute attention deficits, altered consciousness, and fluctuating cognitive dysfunction, typically triggered by multifactorial causes such as physical illness, medication use, or postoperative stress . As the most common complication in hospitalized patients, delirium is highly prevalent among elderly surgical populations, with postoperative delirium (POD) occurring in 7.5%-27.5% of cases, and rates rising to 50%-70% in intensive care unit (ICU) patients . Its onset is closely associated with poor prognoses, including long-term postoperative cognitive decline , increased mortality, prolonged hospitalization, and elevated healthcare costs (annual costs in the United States ranging from 38billionto152 billion) . Early prevention and screening of POD are therefore critical to improving patient outcomes and reducing healthcare burdens. Surgical patients' oral health issues exhibit multifactorial pathogenesis: intrinsic factors (e.g., age-related tooth loss, malnutrition-induced mucosal repair impairment, and chewing dysfunction due to reduced skeletal muscle mass) and iatrogenic factors (e.g., endotracheal intubation trauma, salivary secretion suppression from analgesics, and inadequate perioperative oral care). Poor oral health in hospitalized patients is often attributable to aging, physical dependence, cognitive decline, malnutrition, low skeletal muscle mass/strength, and comorbidities. The recently proposed concept of "Oral Fr…

This description comes directly from the study's public registry record.

Talk to the study team

Aimin Shao, master  ·  18796080248  ·  1224103064@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Xinhua hospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06969092