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Study identifier: NCT06966934 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Nasopharyngeal Airway Combined With Nasal High-flow Oxygen Therapy During Painless Gastroscopy in Obesity Patients

Condition: Hypoxia · Obesity · Gastrostomy  ·  Sponsor: Nanjing First Hospital, Nanjing Medical University

PhaseNA
Planned participants364
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Gastroscopy is a commonly used, direct, and reliable method for screening and diagnosing digestive tract diseases. However, as an invasive examination, it can cause adverse reactions such as pain, nausea, vomiting, and choking cough in patients. Compared with ordinary gastroscopy, painless gastroscopy offers higher comfort and satisfaction for patients and greater convenience for endoscopists during operation. The most common complication of painless gastroscopy diagnosis and treatment is hypoxia. High-flow nasal cannulala (HFNC) provides a higher oxygen concentration and flow rate than an ordinary nasal catheter. It has the functions of heating and humidifying, which can relieve the pressure on the nasal mucosa cilia, keep the airway unobstructed and moist, and reduce the risk of epistaxis. Due to changes in airway anatomical structures such as fat accumulation in the head and neck and hyperplasia of oropharyngeal soft tissues, obese patients are more prone to hypoxia during gastroscopy under sedation. Therefore, HFNC is often used to reduce the occurrence of hypoxia. The nasopharyngeal airway (NPA) is used to maintain the patency of the upper respiratory tract and is suitable for patients with spontaneous breathing but partial obstruction of the upper respiratory tract. It is worth exploring how effective the combination of HFNC and NPA is in improving hypoxemia in obese patients during sedation.

This description comes directly from the study's public registry record.

Talk to the study team

Jing Hu, Master  ·  15366110201  ·  hujingmz@163.com

Tao Shan, Master  ·  18852095135  ·  858727933@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Nanjing First HospitalNanjing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06966934