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Study identifier: NCT06966804 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparison of Alpha Blockers (Terazosin and Tamsulosin) in Reducing Ureteral Stent Related Symptoms

Condition: Stent Related Symptoms  ·  Sponsor: Penang Hospital, Malaysia

PhasePhase 3
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare how well Terazosin, Tamsulosin and standard care (no alpha-blocker) reduce urinary symptoms after ureteral stent placement. This trial also learn about the safety of these two study medications. Main objective: • To compare how well Terazosin, Tamsulosin and standard of care reduce post-stenting urinary symptoms. Secondary objectives: * To assess differences in Body pain, General health, Work performance, Sexual matters, and Additional problems using a questionnaire (USSQ). * To assess differences in side effects. After stent placement, subjects will be randomly assigned to one of three groups: 1. Terazosin (alpha-blocker) for 14 days 2. Tamsulosin (alpha-blocker) for 14 days 3. Standard of care (no alpha-blocker). All subjects will be discharged with standard pain-killers and a diary to track usage. Subjects in Terazosin and Tamsulosin groups will receive respective study medications to complete 14 days course of treatment. Follow-Up: * Day 7: A phone call will check medication use and any side effects. * Day 15: Clinic visit for stent removal (standard practice). Subjects will complete the USSQ questionnaire, and medication compliance will be reviewed. End of study: Final phone call to check for any additional side effects.

This description comes directly from the study's public registry record.

Talk to the study team

Yeon Wee Ooi  ·  6042225333  ·  raymondooi09@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Sultanah Bahiyah Hospital, Alor SetarAlor Star, Kedah, MalaysiaRecruiting
Hospital Pulau PinangGeorge Town, Pulau Pinang, MalaysiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06966804