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Study identifier: NCT06966232 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Prophylactic or Preemptive Entecavir in Patients With Gastrointestinal Cancer Who Are Inactive Hepatitis B Carriers

Condition: Gastrointestinal Cancers  ·  Sponsor: Sun Yat-sen University

PhasePhase 3
Planned participants136
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

There has been no report on whether the patients with gastrointestinal cancer who are also inactive hepatitis B carriers should receive prophylactic use or preemptive use of an anti-viral drug entecavir during anti-tumor therapy. This open, multicentre, phase 3, randomized controlled clinical trial aims to compare the impact of the prophylactic use or preemptive use of an anti-viral drug entecavir on the outcomes of patients with gastrointestinal cancer who are also inactive hepatitis B carriers during chemotherapy or immunotherapy and the subsequent follow-ups, including two cohorts of chemotherapy and immunotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Xu Rui-hua, M.D. Ph.D  ·  +86-20-87343008  ·  xurh@sysucc.org.cn

Wang Feng, M.D. Ph.D  ·  +86-18620880867  ·  fengwang@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06966232