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Study identifier: NCT06966154 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase Ib/II Clinical Study Evaluating the Safety and Efficacy of Tislelizumab in Combination With Golidocitinib and Selinexor for the Treatment of R/R NKTCL

Condition: Natural Killer/T-cell Lymphoma · Relapsed or Refractory Lymphoma Including ENKL  ·  Sponsor: Fudan University

PhasePhase 1/Phase 2
Planned participants68
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This open-label, multicenter Ib/II phase clinical trial investigates the safety, tolerability, and preliminary efficacy of tislezumab (anti-PD-1 monoclonal antibody), golidocitinib (JAK1/STAT3 signaling pathway inhibitor), and selinexor (selective inhibitor of nuclear export, XPO1 antagonist) in patients with relapsed/refractory extranodal natural killer/T-cell lymphoma (R/R ENKTL) progressing after ≥1 line of L-asparaginase-containing chemotherapy or chemoradiotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Rong Tao, MD & PhD  ·  008621-64175590  ·  hkutao@hotmail.com

Chuanxu Liu, MD  ·  008621-64175590  ·  liuchaunxu@shca.or.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Dept of lymphoma and medical oncology, Shanghai Cancer CenterShanghai, Shangai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06966154