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Study identifier: NCT06965101 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

To Determine Whether it is Feasible to Treat Patients Requiring Urgent Radiotherapy Diagnosed With Metastatic Cord Compression (MSCC) on the Magnetic Resonance Linear Accelerator (MRL) in a Single Appointment and Compare it to the Standard of Care Radiotherapy Pathway

Condition: Metastatic Spinal Cord Compression  ·  Sponsor: The Christie NHS Foundation Trust

PhaseNA
Planned participants72
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to understand whether the Magnetic Resonance Linear Accelerator (MRL) could expedite Radiotherapy treatment for Metastatic Cord Compression (MSCC) by removing the need for a planning CT (pCT) scan prior to treatment. Radiotherapy will be delivered in one appointment on the MRL and compared to the standard of care of two appointments: a CT scan and a Radiotherapy appointment. The main questions it aims to answer are: * Can the MRL deliver successful treatment of MSCC in a single 1-hour appointment? * Can the MRL treat participants within 24 hours from the doctor's decision to treat? * Did it take less time from consent to completion of treatment when patients were treated on the MRL? * Do the questionnaire scores reflect satisfaction with treatment on the MRL? Researchers will compare treatment on the MRL in one appointment to a group receiving standard of care radiotherapy in two appointments. Participants in both groups will receive the same prescription of 8Gray (Gy) in one treatment (fraction) delivered with one posterior-anterior beam as per our department policies and national standards. Participants will be asked to complete an optional questionnaire prior to treatment to monitor the diversity of the study population. This questionnaire is anonymised, no personal data that could identify a participant is collected on this questionnaire. After treatment participants will be asked to complete an experience questionnaire, to assess t…

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trial Radiographer  ·  +441614468386  ·  the-christie.radiotherapyclinicaltrials@nhs.net

Alice Greenwood-Wilson  ·  +441614468386  ·  alice.greenwoodwilson@nhs.net

Always discuss trial participation with your own doctor first.

Locations (1)

The Christie NHS Foundation TrustManchester, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06965101