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Study identifier: NCT06964009 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

DT2216 + Paclitaxel in Platinum-Resistant Ovarian Cancer

Condition: Ovarian Cancer · Ovarian Carcinoma · Recurrent Ovary Cancer  ·  Sponsor: Elizabeth Stover, MD, PhD

PhasePhase 1
Planned participants30
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this research study is determining the highest dose of the study drug DT2216 in combination with paclitaxel that can be safely and tolerably administered in recurrent ovarian cancer. The names of the study drugs involved in this study are: * DT2216 (a type of proteolysis-targeting chimera degrader of BCL-XL protein) * Paclitaxel (a type of antimicrotubule agent)

This description comes directly from the study's public registry record.

Talk to the study team

Elizabeth Stover, MD, PhD  ·  617-632-6866  ·  elizabeth_stover@dfci.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (3)

Beth Israel Deaconess Medical Center (BIDMC)Boston, Massachusetts, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Brigham and Women's HospitalBoston, Massachusetts, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06964009