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Study identifier: NCT06960954 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

PIVKA-II for Predicting Portal Vein Thrombosis in Hepatocellular Carcinoma

Condition: Hepato Cellular Carcinoma (HCC) · Portal Vein Tumour Thrombosis  ·  Sponsor: Tanta University

PhaseN/A
Planned participants116
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this cross-sectional observational study is to evaluate the relation between Prothrombin induced by vitamin K absence II (PIVKA-II) and the presence of portal vein tumor thrombosis (PVTT) in hepatocellular carcinoma (HCC) patients. Researchers will compare PIVKA-II serum levels in HCC patients with PVTT and without PVTT. Participants will undergo history-taking, clinical examination, laboratory investigations, PIVKA-II serum level, Child-Pugh classification, Model for End-stage Liver Disease (MELD) score, BCLC staging, abdominal ultrasonography, and Triphasic CT abdomen with contrast or MRI to evaluate tumor site, size, number, and presence of PVTT (a filling defect in the portal vein or its branch to distinguish PVTT or thrombus).

This description comes directly from the study's public registry record.

Talk to the study team

Rania M Elkafoury, MD  ·  +201004672358  ·  rania.elkafoury@med.tanta.edu.eg

Nabila A Elgazzar, MD  ·  00201288585733  ·  nabilaelgazzar@med.tanta.edu.eg

Always discuss trial participation with your own doctor first.

Locations (1)

Tanta University HospitalsTanta, Gharbyea, EgyptRecruiting

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Source record: clinicaltrials.gov/study/NCT06960954