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Study identifier: NCT06960928 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Low Dose Sirolimus in People With Post-Acute Sequelae of COVID-19 (PASC) Long COVID-19

Condition: Long COVID-19  ·  Sponsor: Icahn School of Medicine at Mount Sinai

PhasePhase 3
Planned participants80
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The study is conducted in New York, New York at The Cohen Center for Recovery from Complex Chronic Illness at Mount Sinai. This is an IND-exempt, off-label, multi-ascending, randomized, placebo-controlled clinical trial of sirolimus (also known as rapamycin) in adults with Long COVID. There are 2 arms: Sirolimus and Placebo. This study aims to evaluate the efficacy of Sirolimus in adults with Long COVID. Efficacy will be evaluated by measuring patient-reported outcomes in response to Sirolimus.

This description comes directly from the study's public registry record.

Talk to the study team

David Putrino, PT, PhD  ·  212-241-7658  ·  coreresearch@mountsinai.org

Mackenzie Doerstling, MPH  ·  212-241-7658  ·  coreresearch@mountsinai.org

Always discuss trial participation with your own doctor first.

Locations (1)

Icahn School of Medicine at Mount SinaiNew York, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06960928