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Study identifier: NCT06960902 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of the Determinants of Coronary Atherosclerosis in Familial Hypercholesterolemia (ATHERO-FH Study)

Condition: Familial Hypercholesterolemias · Atherosclerotic Cardiovascular Disease (ASCVD)  ·  Sponsor: Nantes University Hospital

PhaseNA
Planned participants600
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this study (interventional clinical research not involving a health product) is to assess the prevalence of subclinical coronary atherosclerosis diagnosed by coronary CT angiography in heart failure patients in primary prevention, across different levels of cardiovascular risk defined by coronary artery calcium (CAC) score percentiles (based on data from the MESA study): low risk (≤25th percentile for age, sex, and ethnicity), intermediate risk (25th \< CAC ≤ 75th percentile), and high risk (\>75th percentile). The Patients will attend an on-site visit at inclusion (and must undergo a coronary CT angiography within 6 months following this visit), will be contacted by phone at 1 year and 2 years, and will return for an on-site visit at 30 months.

This description comes directly from the study's public registry record.

Talk to the study team

Bertrand CARIOU, Pr  ·  +33 2 53 48 27 10  ·  bertrand.cariou@chu-nantes.fr

Always discuss trial participation with your own doctor first.

Locations (9)

CHU Dijon BourgogneDijon, FranceRecruiting
CHRU LilleLille, FranceNot Yet Recruiting
Hospices Civils de LyonLyon, FranceRecruiting
Hôpital de la Conception, AP-HMMarseille, FranceNot Yet Recruiting
CHU NantesNantes, FranceRecruiting
Hôpital de la Pitié-Salpêtrière, AP-HPParis, FranceRecruiting
Hôpital Saint-Antoine, AP-HPParis, FranceRecruiting
CHU RennesRennes, FranceRecruiting
CHU StrasbourgStrasbourg, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06960902