Condition: Locally Advanced Unresectable Pancreatic Ductal Adenocarcinoma · Stage II Pancreatic Cancer AJCC v8 · Stage III Pancreatic Cancer AJCC v8 · Sponsor: NRG Oncology
This phase III trial compares the effect of dose-escalated radiation therapy to usual care in patients with locally advanced unresectable pancreatic ductal adenocarcinoma who have received an initial 4-6 months of chemotherapy. Usual care options include additional chemotherapy, observation, or standard lower-dose radiation therapy. These treatments may delay tumor growth but have not been shown to improve survival. Radiation therapy uses high energy X-rays to kill cancer cells and shrink tumors. Dose-escalated radiation therapy involves the precise delivery of higher doses to the tumor, often over a shorter period of time. This trial assesses whether using dose-escalated radiation therapy can prolong survival.
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
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| Banner MD Anderson Cancer Center | Gilbert, Arizona, United States | Recruiting |
| Arizona Center for Cancer Care - Gilbert | Gilbert, Arizona, United States | Recruiting |
| Arizona Center for Cancer Care-Peoria | Peoria, Arizona, United States | Recruiting |
| Arizona Center for Cancer Care - Phoenix | Phoenix, Arizona, United States | Recruiting |
| Arizona Center for Cancer Care - Scottsdale | Scottsdale, Arizona, United States | Recruiting |
| Arizona Center for Cancer Care-Surprise | Surprise, Arizona, United States | Recruiting |
| Arizona Center for Cancer Care | Tempe, Arizona, United States | Recruiting |
| NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro | Jonesboro, Arkansas, United States | Recruiting |
| Mission Hope Medical Oncology - Arroyo Grande | Arroyo Grande, California, United States | Recruiting |
| AIS Cancer Center at San Joaquin Community Hospital | Bakersfield, California, United States | Recruiting |
| Alta Bates Summit Medical Center-Herrick Campus | Berkeley, California, United States | Recruiting |
| Mills-Peninsula Medical Center | Burlingame, California, United States | Recruiting |
+ 310 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06958328