Condition: Atrial Fibrillation (AF) · VTE · Sponsor: McMaster University
PAUSE 2 study is a prospective, open-label, blinded-endpoint non-inferiority RCT of PAUSE vs. ASRA management in DOAC treated high risk patients with AF/VTE who need elective high bleed risk surgery/procedure and/or any procedure involving neuraxial anesthesia. The purpose of the PAUSE 2 study is to show that PAUSE management will be as safe (i.e., non-inferior) as ASRA management, with 95% of patients having low/undetectable pre-operative DOAC levels \<30 ng/mL in each group., at the time of surgery/neuraxial.
This description comes directly from the study's public registry record.
James Douketis, MD · 905-522-1155 · jdouket@mcmaster.ca
Melanie St John · stjohm1@mcmaster.ca
Always discuss trial participation with your own doctor first.
| Hartford Health Care | Hartford, Connecticut, United States | Not Yet Recruiting |
| North Shore University Health | Evanston, Illinois, United States | Not Yet Recruiting |
| Brigham and Woman's Hospital | Boston, Massachusetts, United States | Not Yet Recruiting |
| Henry Ford Health Care | Detroit, Michigan, United States | Not Yet Recruiting |
| Northwell Health System | New York, New York, United States | Not Yet Recruiting |
| Thomas Jefferson University Hospital | Philadelphia, Pennsylvania, United States | Not Yet Recruiting |
| University of Leuven | Leuven, Belgium, Belgium | Not Yet Recruiting |
| Winnipeg Health Sciences Center | Winnipeg, Manitoba, Canada | Not Yet Recruiting |
| St. Joesph's Healthcare | Hamilton, Ontario, Canada | Recruiting |
| Juravinski | Hamilton, Ontario, Canada | Not Yet Recruiting |
| The Ottawa Hospital | Ottawa, Ontario, Canada | Not Yet Recruiting |
| L'Hospital Montfort | Ottawa, Ontario, Canada | Not Yet Recruiting |
+ 2 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06957366