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Study identifier: NCT06953999 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase III Study of Ivonescimab + Chemo With/Without AK117 in Metastatic Pancreatic Cancer

Condition: Pancreatic Cancer  ·  Sponsor: Akeso

PhasePhase 3
Planned participants999
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a Phase 3, randomized, double-blind clinical trial aimed at evaluating the efficacy and safety of Ivonescimab plus chemotherapy with or without AK117 versus placebo plus chemotherapy in patients with metastatic pancreatic cancer. The study seeks to determine whether the addition of Ivonescimab and/or AK117 improves clinical outcomes compared to standard chemotherapy alone. Participants will be randomly assigned to receive either Ivonescimab with/without AK117 or placebo, both in combination with chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Wenting Li  ·  +86-18116403289  ·  wenting01.li@akesobio.com

Always discuss trial participation with your own doctor first.

Locations (3)

Harbin Medical University Cancer HospitalHarbin, Heilongjiang, ChinaRecruiting
Fudan University Shanghai Cancer CenterShanghai, Shanghai Municipality, ChinaRecruiting
Zhejiang Cancer HospitalHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06953999