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Study identifier: NCT06953882 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Impact of Omitting Chemo Based on Patient's Selection for ER-Positive, HER2-Negative Breast Cancer With Ribociclib and Endocrine Therapy

Condition: HER2 Negative Breast Cancer  ·  Sponsor: Yale University

PhasePhase 2
Planned participants140
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase II, two-arm, single center, patient preference study designed to evaluate the impact of omitting adjuvant chemotherapy in moderate to high-anatomical risk, low-genomic risk (men or premenopausal women T2-3N0 and RS 16-25, or T1-3N1-2 and RS ≤ 25, and postmenopausal women T2-3N0 and RS 26-30, or T1-3N1 and RS 26-30, or T1-3N2 and RS ≤ 25),

This description comes directly from the study's public registry record.

Talk to the study team

Stephanie Ladd  ·  954-895-0576  ·  stephanie.ladd@yale.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Yale UniversityNew Haven, Connecticut, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06953882