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Study identifier: NCT06953466 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome

Condition: Netherton Syndrome  ·  Sponsor: Quoin Pharmaceuticals

PhasePhase 2/Phase 3
Planned participants8
Who can joinAll sexes, 14 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial (via an expanded access Treatment Protocol) is to learn if QRX003 (an investigational drug) applied topically to the skin (including up to the entire body \[except the scalp\]) works to treat the genetic disease Netherton syndrome. It will also learn about the safety of QRX003. The main questions the trial aims to answer are: 1. Does QRX003 impact the clinical presentation of NS in adults and minors by improving the clinical symptoms (diseased skin area, itch, and discomfort; based on clinical scoring, subject self-assessment, and other criteria)? 2. What medical problems do participants have when taking QRX003? 3. What percent of subjects will require rescue therapy? Participants will: Take drug QRX003 twice daily (applied topically to all affected areas of the body excluding the scalp) for 3 months, visit the clinic once every 4-6 weeks for checkups and tests, and to keep a dosing diary that records the times they applied the drug.

This description comes directly from the study's public registry record.

Talk to the study team

TI Clinical Research  ·  858-571-1800  ·  clinicalresearch@therapeuticsinc.com

Oleg G Khatsenko  ·  858-571-1800  ·  okhatsenko@therapeuticsinc.com

Always discuss trial participation with your own doctor first.

Locations (1)

Northwestern Memorial HospitalChicago, Illinois, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06953466